head to head · open source
ComfyUI vs wisp-science
ComfyUI has 133,963 GitHub stars, 15,874 forks, 4,894 open issues and last shipped today. wisp-science has 1,155 stars, 118 forks, 10 open issues and last shipped today. ComfyUI leads on adoption by 11,499% (133,963 vs 1,155 stars). ComfyUI is written in Python under GPL-3.0; wisp-science is written in Rust under AGPL-3.0. ComfyUI has attracted 12% as many forks as stars, wisp-science 10%. wisp-science was the more recently maintained of the two, and both are self-hostable with no licence fee.
Two open source projects, one decision. Both are free and self-hostable — the differences are community size, license terms, language stack and release pace.
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Side by side
| ComfyUI | wisp-science | |
|---|---|---|
| GitHub stars | ★ 134K | ★ 1.2K |
| License | GPL-3.0 | AGPL-3.0 |
| Written in | Python | Rust |
| Last push | 2026-09-20 | 2026-09-20 |
| Forks | ⑂ 16K | ⑂ 118 |
| Self-hosting | Yes | Yes |
| Data ownership | Your server | Your server |
pick ComfyUI if
- You weight community size — 134K stars and counting
- You want the GPL-3.0 license terms
- Your stack matches Python
- You value the larger contributor base for long-term maintenance
pick wisp-science if
- You want the wisp-science feature set and don't need the biggest community
- You prefer the AGPL-3.0 license terms
- Your stack matches Rust
- You evaluated both and wisp-science fits your workflow better
About ComfyUI
ComfyUI is a GPL 3.0 licensed Python and PyTorch node graph application, local API, and backend for running diffusion models across image, video, audio, 3D, and text workflows, built for visual professionals who want control over every model, parameter, and output, and for developers who embed those workflows into production pipelines.
read the full ComfyUI overview →
About wisp-science
Wisp Science is an open source, local first desktop AI research workbench that gives scientists and research teams an agentic workspace for literature search, Python and R execution, scientific database queries, and manuscript preparation, all running against their own machines.
read the full wisp-science overview →
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Frequently asked questions
Is ComfyUI or wisp-science more popular?
ComfyUI has 133,963 GitHub stars and wisp-science has 1,155. ComfyUI has the larger community by that measure.
Are ComfyUI and wisp-science free?
Both are open source. ComfyUI is licensed under GPL-3.0 and wisp-science under AGPL-3.0. Neither carries a licence fee.
What is the difference between ComfyUI and wisp-science?
ComfyUI is written in Python and wisp-science in Rust. The practical differences are community size, licence terms, language stack and release cadence — all compared in the table above.
Which should I choose, ComfyUI or wisp-science?
Choose ComfyUI if you want the larger community (133,963 stars) or its GPL-3.0 licence terms. Choose wisp-science if its feature set, stack or AGPL-3.0 licence fits better. Both are self-hostable.